陈苑 植物免疫识别和抗病机制实验室主任
邮箱：yuan.chen@pku-iaas.edu.cn
研究方向：植物生殖发育，植物与微生物互作
个人简介：
2005年09月–2012年12月，中国科学院植物研究所，博士
2013年01月–2016年06月，加州大学伯克利分校、美国农业部植物基因研究中心，博士后
2016年07月–2017年03月，美国ALSTEM公司，科学家
2017年05月–2020年05月，加州大学伯克利分校、美国农业部植物基因研究中心，博士后
2020年12月–至今，北京大学现代农业研究院，研究员、课题组长(Principal Investigator /PI)
重要荣誉及奖励：
周凯旋基金会杰出青年女科学家奖Chau Hoi Shuen Foundation Outstanding Young Women Scientist
加州大学Tang基金会杰出学者UC Berkeley Tang Distinguished Scholarship
2005年09月–2012年12月，中国科学院植物研究所，博士
2013年01月–2016年06月，加州大学伯克利分校、美国农业部植物基因研究中心，博士后
2016年07月–2017年03月，美国ALSTEM公司，科学家
2017年05月–2020年05月，加州大学伯克利分校、美国农业部植物基因研究中心，博士后
2020年12月–至今，北京大学现代农业研究院，研究员、课题组长(Principal Investigator /PI)
重要荣誉及奖励：
周凯旋基金会杰出青年女科学家奖Chau Hoi Shuen Foundation Outstanding Young Women Scientist
加州大学Tang基金会杰出学者UC Berkeley Tang Distinguished Scholarship
主要研究领域：
针对我国粮食安全的重大需求和生命科学的前沿问题，本课题组主要围绕农作物和园艺作物中两个重点问题展开。一个是探寻作物生长发育中影响产量和品质的重要性状：株型发育（分蘖、株高、穗型等）和籽粒形成（花/穗建成、籽粒发育、品质等）。二是围绕 “作物的免疫识别和抗病机制” 这一关键科学问题，以小麦赤霉病，辣椒疫病，十字花科根肿病为研究方向，探索细菌、卵菌、真菌等病原微生物如何逃避宿主免疫系统的识别，植物如何进化出复杂的免疫系统来抵抗病原菌的侵染。同时，课题组还在土壤微生物群落多样性与植物抗病力方面进行探索，为绿色农业和可持续发展农业提供理论支持和技术支撑。
发表论文：
1. Yuan Chen, Claire Bendix, Jennifer Lewis. Comparative genomics screen identifies
microbe-associated molecular patterns from Candidatus Liberibacter sp. that elicit immune
responses in citrus. Molecular Plant-Microbe Interactions. 2020.
2. Yuan Chen, Ting Zou, Sheila McCormick*. S-adenosylmethionine synthetase is required in
pollen germination and pollen tube growth in Arabidopsis. Plant Physiology. 2016
Sep;172(1):244-53.
3. Yuan Chen, Yunyuan Xu, Wei Luo, Wenxuan Li, Na Chen, Dajian Zhang and Kang
Chong*. The F-box protein OsFBK12 targets OsSAMS1 for degradation and affects pleiotropic
phenotypes including leaf senescence in rice. Plant Physiology. 2013, Vol.163, pp. 1673–1685
4. Yuan Chen, Fei Li, Yan Ma, Kang Chong and Yunyuan Xu*. Overexpression of OrbHLH001, a
putative helix–loop–helix transcription factor, causes increased expression of AKT1
maintains ionic balance under salt stress in rice. Journal of Plant Physiology. 2013,170(1):93-100
5. Huan Zhang, Yuhong Cao, Dawei Xu, Natalie S Got, Gozde S Demirer, Stefano Cestellos
Blanco, Yuan Chen, Makita Landry, Peidong Yang. Gold Nanoclusters Meditated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown. Nano Letters, 2021, 21, 13, 5859–5866.
6. Kangxin Li, Jinying Wang, Lu Qiao, Ruyi Zheng, Yiqun Ma, Yuan Chen, Xiaobo Hou, Yanjun
Du, Jianguo Gao, Hui Liu*. Diversity of reproductive phenology among subtropical grasses is
constrained by evolution and climatic niche. Frontiers in Ecology and Evolution. 2020
7. Xuepiao Pu, Chunmei Meng , Weili Wang, Siyu Yang, Yuan Chen, Qingjun Xie, BinYu,
Yunfeng Liu*. DSP1 and DSP4 act synergistically in snRNA 3’ end maturation and pollen growth.
Plant Physiology. 2019.
8. Yunfeng Liu, Shengjun Li, Yuan Chen, Athen N. Kimberlin, Edgar B. Cahoon and Bin Yu.
snRNA 3’ end processing by a CPSF73-containing complex essential for development in
Arabidopsis. PLOS Biology. 2016.
9. Hua Jiang, Jun Yi, Leonor C. Boavida, Yuan Chen, Jörg D. Becker, Claudia Köhler, and Sheila
McCormick*.Intercellular communication in Arabidopsis thaliana pollen discovered via AHG3
transcript movement from the vegetative cell to sperm. PNAS. 2015, Oct 27;112(43):13378-83
代表性专利：
种康、陈苑、陈娜、徐云远, 与植物种子大小相关的蛋白及其编码基因与应用,
专利号: CN102336824 A
microbe-associated molecular patterns from Candidatus Liberibacter sp. that elicit immune
responses in citrus. Molecular Plant-Microbe Interactions. 2020.
2. Yuan Chen, Ting Zou, Sheila McCormick*. S-adenosylmethionine synthetase is required in
pollen germination and pollen tube growth in Arabidopsis. Plant Physiology. 2016
Sep;172(1):244-53.
3. Yuan Chen, Yunyuan Xu, Wei Luo, Wenxuan Li, Na Chen, Dajian Zhang and Kang
Chong*. The F-box protein OsFBK12 targets OsSAMS1 for degradation and affects pleiotropic
phenotypes including leaf senescence in rice. Plant Physiology. 2013, Vol.163, pp. 1673–1685
4. Yuan Chen, Fei Li, Yan Ma, Kang Chong and Yunyuan Xu*. Overexpression of OrbHLH001, a
putative helix–loop–helix transcription factor, causes increased expression of AKT1
maintains ionic balance under salt stress in rice. Journal of Plant Physiology. 2013,170(1):93-100
5. Huan Zhang, Yuhong Cao, Dawei Xu, Natalie S Got, Gozde S Demirer, Stefano Cestellos
Blanco, Yuan Chen, Makita Landry, Peidong Yang. Gold Nanoclusters Meditated Delivery of siRNA to Intact Plant Cells for Efficient Gene Knockdown. Nano Letters, 2021, 21, 13, 5859–5866.
6. Kangxin Li, Jinying Wang, Lu Qiao, Ruyi Zheng, Yiqun Ma, Yuan Chen, Xiaobo Hou, Yanjun
Du, Jianguo Gao, Hui Liu*. Diversity of reproductive phenology among subtropical grasses is
constrained by evolution and climatic niche. Frontiers in Ecology and Evolution. 2020
7. Xuepiao Pu, Chunmei Meng , Weili Wang, Siyu Yang, Yuan Chen, Qingjun Xie, BinYu,
Yunfeng Liu*. DSP1 and DSP4 act synergistically in snRNA 3’ end maturation and pollen growth.
Plant Physiology. 2019.
8. Yunfeng Liu, Shengjun Li, Yuan Chen, Athen N. Kimberlin, Edgar B. Cahoon and Bin Yu.
snRNA 3’ end processing by a CPSF73-containing complex essential for development in
Arabidopsis. PLOS Biology. 2016.
9. Hua Jiang, Jun Yi, Leonor C. Boavida, Yuan Chen, Jörg D. Becker, Claudia Köhler, and Sheila
McCormick*.Intercellular communication in Arabidopsis thaliana pollen discovered via AHG3
transcript movement from the vegetative cell to sperm. PNAS. 2015, Oct 27;112(43):13378-83
代表性专利：
种康、陈苑、陈娜、徐云远, 与植物种子大小相关的蛋白及其编码基因与应用,
专利号: CN102336824 A