宋宝兴 禾本科优异基因挖掘与利用课题组组长
Email：baoxing.song@pku-iaas.edu.cn
研究方向：群体和多物种优异基因的挖掘，植物的环境适应性，群体遗传学
个人简介：
2022-至今 北京大学现代农业研究院 研究员
2018-2022 美国康奈尔大学 博士后
2014-2018 德国马克斯·普朗克植物育种研究所（科隆大学授予学位） 博士
2010-2013 西北农林科技大学 硕士
2006-2010 郑州大学 学士
主要学术兼职和荣誉:
入选国家高层次人才青年项目
BMC Genomics 期刊编辑
New Crops 期刊编委
iMeta 期刊青年编委
Beverage Plant Research 期刊青年编委
Sigma Xi 科学研究荣誉学会会员
中国生物工程学会计算生物学与生物信息专业委员会委员
研究领域：
本课题组聚焦禾本科小麦等主粮作物，利用多物自然群体与禾本科野生近缘物种资源，挖掘耐逆、环境适应性及农艺性状关键优异基因；解析物种进化与遗传变异规律。通过多学科交叉技术手段，实现优异基因的功能解析与育种高效利用。致力于通过农作物和野生物种的遗传研究，实现高效、环境友好、并可持续的农业发展模式。
实验室代码托管请见：
http://github.com/baoxingsong/
研究组致力于培养善于独立思考、勇于探索、具有领导力的青年科学家。欢迎理想远大，聪明勤奋、品格坚韧、能够自我管理的学生、青年学者和业界人士咨询、加盟！
代表性论文：（#，equal contribution; *，corresponding）
1. Shuai Wang, Merritt Khaipho-Burch, Lynn C. Johnson, Zachary R. Miller, Peter Bradbury, Doug Speed, William J. Allen, M. Cinta Romay, Jiquan Xue, Edward S. Buckler*, Guillaume P. Ramstein*, Baoxing Song*. Predicted protein 3D structure provides essential insights into the genetic architecture underlying phenotypic diversity in maize. Genome Research. 2026
2. Xiaodong Li, Yan Zhang, Rui Zhang, Zhiyu Liu, Jiquan Xue, Baoxing Song* . quota_Anchor: a strand and whole genome duplication–aware collinear gene identification tool. aBIOTECH. 2026
3. Huawei Feng, Wenjuan Fan, Min Liu, Jiaqian Huang, Bosheng Li, Qing Sang* and Baoxing Song*. Cross-species single-nucleus analysis reveals the potential role of whole-genome duplication in the evolution of maize flower development. BMC Genomics. 2025
4. Jinwei Yang#, Hongna Li#, Mengyu Li#, Rui Song#, Tao Shen, Guiping Wang, Dong Xu, Ming Hao, Aolin Jia, Shams ur Rehman, Lei Hua, Yanyan Liang, Cheng Chi, Caixia Lan, XingWang Deng, Jorge Dubcovsky, Baoxing Song*, Xiaodong Wang*, Shisheng Chen*. Genome-assisted identification of wheat leaf rust resistance gene Lr.ace-4A/Lr30. Nature Communications. 2025
5. Weiwei Fang, Haiying Yang, Huawei Feng, Baoxing Song*, Qing Sang*. Genome level identification of transcription start sites by nanoCAGE sequence in soybean. Scientific Data. 2025
6. Huafeng Zhou, Xiaoquan Su* and Baoxing Song*. ACMGA: a reference-free multiple-genome alignment pipeline for plant species. BMC Genomics. 2024
7. Guang Yang#, Yan Pan#, Wenqiu Pan#, Qingting Song, Ruoyu Zhang, Wei Tong, Licao Cui, Wanquan Ji, Weining Song, Baoxing Song*, Pingchuan Deng*, Xiaojun Nie*. Combined GWAS and eGWAS reveals the genetic basis underlying drought tolerance in emmer wheat (Triticum turgidum L.). New Phytologist. 2024
8. Baoxing Song*, Edward S. Buckler, Michelle C. Stitzer*. New whole-genome alignment tools are needed for tapping into plant diversity. Trends in Plant Science. 2023
9. Shuai Wang, Qinlin Xu, Baoxing Song*. Applying AnchorWave to Address Plant Genome Alignment. Bio-protocol. 2023
10. Baoxing Song*, Santiago Marco-Sola, Miquel Moreto, Lynn Johnson, Edward S. Buckler*, Michelle C. Stitzer*. AnchorWave: Sensitive alignment of genomes with high sequence diversity, extensive structural polymorphism, and whole-genome duplication. PNAS. 2022
11. Fen Wang*#, Baohui Zhang#, Di Wen#, Rong Liu, Xinzhuan Yao, Zhi Chen, Ren Mu, Huimin Pei, Min Liu, Baoxing Song* and Litang Lu*. Chromosome-scale genome assembly of Camellia sinensis combined with multi-omics provides insights into its responses to infestation with green leafhoppers. Frontiers in Plant Science. 2022
12. Fen Wang, Zhi Chen, Huimin Pei, Zhiyou Guo, Di Wen, Rong Liu, Baoxing Song*. Transcriptome profiling analysis of tea plant (Camellia sinensis) using Oxford Nanopore long-read RNA-Seq technology. Gene. 2021
13. Baoxing Song*, Edward S. Buckler, Hai Wang, Yaoyao Wu, Evan Rees, Elizabeth A. Kellogg, Daniel J. Gates, Merritt Khaipho-Burch, Peter J. Bradbury, Jeffrey Ross-Ibarra, Matthew B. Hufford and M. Cinta Romay*. Conserved noncoding sequences provide insights into regulatory sequence and loss of gene expression in maize. Genome Research. 2021
14. Baoxing Song*#, Qing Sang#, Hai Wang, Huimin Pei, XiangChao Gan* and Fen Wang*. Complement Genome Annotation Lift Over Using a Weighted Sequence Alignment Strategy. Frontiers in Genetics. 2019
15. Baoxing Song, Richard Mott, Xiangchao Gan*. Recovery of novel association loci in Arabidopsis thaliana and Drosophila melanogaster through leveraging INDELs association and integrated burden test. PLoS Genetics. 2018
16. Fen Wang#, Baoxing Song#, Xing Zhao, Yaotian Miao, Dengyun Li, Na Zhou, Pengfei Jiang, Qing Sang, Jingfei Huang, Deli Zhang*. Prediction and analysis of the protein-protein interaction networks for chickens, cattle, dogs, horses and rabbits. Current bioinformatics. 2016
17. Baoxing Song#, Fen Wang#, Yang Guo, Qing Sang, Min Liu, Dengyun Li, Wei Fang, Deli Zhang. Protein–protein interaction network‐based detection of functionally similar proteins within species. Proteins: Structure, Function, and Bioinformatics. 2012
18. Baoxing Song, Xiaoquan Su, Jian Xu, Kang Ning*. MetaSee: an interactive and extendable visualization toolbox for metagenomic sample analysis and comparison. PLoS One. 2012
19. Shifeng Cheng, Cong Feng, Luzie U. Wingen, Hong Cheng, Andrew B. Riche, Mei Jiang, Michelle Leverington-Waite, Zejian Huang, Sarah Collier, Simon Orford, Xiaoming Wang, Rajani Awal, Gary Barker, Tom O’Hara, Clare Lister, Ajay Siluveru, Jesús Quiroz-Chávez, Ricardo H. Ramírez-González, Ruth Bryant, Simon Berry, Urmil Bansal, Harbans S. Bariana, Malcolm J. Bennett, Breno Bicego, Lorelei Bilham, James K. M. Brown, Amanda Burridge, Chris Burt, Milika Buurman, March Castle, Laetitia Chartrain, Baizhi Chen, Worku Denbel, Ahmed F. Elkot, Paul Fenwick, David Feuerhelm, John Foulkes, Oorbessy Gaju, Adam Gauley, Kumar Gaurav, Amber N. Hafeez, Ruirui Han, Richard Horler, Junliang Hou, Muhammad S. Iqbal, Matthew Kerton, Ankica Kondic-Spica, Ania Kowalski, Jacob Lage, Xiaolong Li, Hongbing Liu, Shiyan Liu, Alison Lovegrove, Lingling Ma, Cathy Mumford, Saroj Parmar, Charlie Philp, Darryl Playford, Alexandra M. Przewieslik-Allen, Zareen Sarfraz, David Schafer, Peter R. Shewry, Yan Shi, Gustavo A. Slafer, Baoxing Song, Bo Song, David Steele, Burkhard Steuernagel, Phillip Tailby, Simon Tyrrell, Abdul Waheed, Mercy N. Wamalwa, Xingwei Wang, Yanping Wei, Mark Winfield, Shishi Wu, Yubing Wu, Brande B. H. Wulff, Wenfei Xian, Yawen Xu, Yunfeng Xu, Quan Yuan, Xin Zhang, Keith J. Edwards, Laura Dixon, Paul Nicholson, Noam Chayut, Malcolm J. Hawkesford, Cristobal Uauy, Dale Sanders, Sanwen Huang & Simon Griffiths. Harnessing landrace diversity empowers wheat breeding. Nature. 2024
20. Yaoyao Wu, Dawei Li, Yong Hu, Hongbo Li, Guillaume P Ramstein, Shaoqun Zhou, Xinyan Zhang, Zhigui Bao, Yu Zhang, Song Baoxing, Yao Zhou, Yongfeng Zhou, Edeline Gagnon, Tiina Särkinen, Sandra Knapp, Chunzhi Zhang, Thomas Städler, Edward S Buckler, Sanwen Huang*. Phylogenomic discovery of deleterious mutations facilitates hybrid potato breeding. Cell. 2023