邮箱：yan.xue@pku-iaas.edu.cn

 研究方向：辣椒抗逆机制研究及作物改良

研究领域：

        全球气候变化以及大规模的单一种植，使得作物更频繁的受到温度和疾病的胁迫。温度胁迫影响植物生长发育的每个阶段，造成严重减产；且高温高湿环境更容易导致病毒病的大规模爆发。目前对于病毒病的爆发，我们尚无有效的治理措施。辣椒是我国经济价值最高的作物，其对于温度和病毒极为敏感。本课题组针对辣椒应对高低温胁迫以及病毒病的抗性进行研究。具体研究方向包括：

        1. 品种资源收集和筛选对于高低温和病毒病具有抗性的辣椒品种，并在此基础上通过育种，对辣椒进行品种改良。

        2. 对具有抗性的辣椒品种进行深入的分子机制研究。

发表论文：

       1.Wang, Q.,* Xue, Y.,* Zhang, L.,* Zhong, Z., Feng, S., Wang, C., Xiao, L., Yang, Z., Harris, CJ., Wu, Z., Zhai, J.,Yang, M., Li, S., Jacobsen, SE. and Du, J. (2021) Mechanism of siRNA production by a plant Dicer-RNA complex in dicing-competent conformation. Science, 374:1152-1157.

*Equal contribution

       2.Xue, Y.*, Zhong Z.*, Harris CJ.*, Gallego-Bartolomé, J., Wang, M., Picard, C., Cao, X., Hua, S., Kwok, I., Feng, S., Jami-Alahmadi, Y., Sha, J., Gardiner, J., Wohlschlegel, J. and Jacobsen, SE. (2021) Arabidopsis MORC proteins function in the efficient establishment of RNA directed DNA methylation. Nature Communications, 12:4292.

      3.Jiang, Z., Zhou, X., Tao, M., Yuan, Y., Liu, L., Wu, F., Wu, X., Xiang, Y., Niu, Y., Liu, F., Li, C., Ye, R., Byeon, B., Xue, Y., Zhao, H., Wang, S., Crawford, B., Johnson, M., Hu, C., Pei, C., Zhou, W., Swift, G., Zhang, H., Vo-Dinh, T., Hu, Z., Siedow, J. and Pei, Z. (2019) Plant cell-surface GIPC sphingolipids sense salt to trigger Ca²⁺ influx. Nature, 572: 341-346.

       4.Kim, HJ., Yen, L, Wongpalee, SP., Kirshner, JA., Mehta, N., Xue, Y., Johnston, JB., Burlingame, AL., Kim, JK., Loparo JJ., and Jacobsen, SE. (2019). The Gene-Silencing Protein MORC-1 Topologically Entraps DNA and Forms Multimeric Assemblies to Cause DNA Compaction. Molecular Cell, 75: 700-71

       5.Harris, CJ., Scheibe, M., Wongpalee, SP., Liu, W., Cornett, EM., Vaughan, RM., Li, X., Chen, W., Xue, Y., Zhong, Z., Yen, L., Barshop, WD., Rayatpisheh, S., Gallego-Bartolome, J., Groth, M., Wang, Z., Wohlschlegel, JA., Du, J., Rothbart, SB., Butter, F., and Jacobsen, SE. (2018). A DNA methylation reader complex that enhances gene transcription. Science, 6419: 1182-1186.

       6.Yuan, F., Yang, H.*; Xue, Y.*; Kong, D., Ye, R., Li, C., Zhang, J., Theprungsirikul, L.,Shrift, T., Krichilsky, B., Johnson, DM., Swift, GB., He, Y., Siedow, JN. and Pei, ZM.(2014). OSCA1 mediates osmotic-stress-evoked Ca²⁺ increases vital for osmosensing inArabidopsis. Nature. 514: 367-371*equal contribution

     7.Jiang, Z., Zhu, S., Ye, R., Xue, Y., Chen, A., An, L. and Pei, ZM. (2013). Relationship between NaCl^- and H2O2-Induced cytosolic Ca²⁺ Increases in response to stress in Arabidopsis. PloS one. 8: 10

       8.Cheung, MY., Xue, Y., Zhou, L., Li, MW., Sun, SSM. and Lam, HM. (2010) An ancient Ploop GTPase in rice is regulated by a higher plant-specific regulatory protein. Journal of Biololgical Chemistry. 285:37359–37369.

      9.Cheung, MY., Zeng, NY., Tong, SW., Li, FWY., Xue, Y., Zhao, KJ., Wang, C., Zhang, Q., Fu, Y., Sun, Z., Sun, SSM. and Lam, HM. (2008) Constitutive expression of a rice GTPase activating protein induces defense responses. New Phytologist. 179:530-545